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Method combining BAC film and positive staining for the characterization of DNA intermediates by dark-field electron microscopy
DNA intermediate structures are formed in all major pathways of DNA metabolism. Transmission electron microscopy (TEM) is a tool of choice to study their choreography and has led to major advances in the understanding of these mechanisms, particularly those of homologous recombination (HR) and repli...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474861/ https://www.ncbi.nlm.nih.gov/pubmed/32913896 http://dx.doi.org/10.1093/biomethods/bpaa012 |