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The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations

Inorganic polyphosphate (polyP) is a morphogenetically active and metabolic energy-delivering physiological polymer that is released from blood platelets. Here, we show that polyP efficiently inhibits the binding of the envelope spike (S)-protein of the coronavirus SARS-CoV-2, the causative agent of...

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Detalles Bibliográficos
Autores principales:	Neufurth, Meik, Wang, Xiaohong, Tolba, Emad, Lieberwirth, Ingo, Wang, Shunfeng, Schröder, Heinz C., Müller, Werner E.G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474874/ https://www.ncbi.nlm.nih.gov/pubmed/32905794 http://dx.doi.org/10.1016/j.bcp.2020.114215

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