Activation of the SARS-CoV-2 Receptor Ace2 through JAK/STAT-Dependent Enhancers during Pregnancy

ACE2 binds the coronavirus SARS-CoV-2 and facilitates its cellular entry. Interferons activate ACE2 expression in pneumocytes, suggesting a critical role of cytokines in SARS-CoV-2 target cells. Viral RNA was detected in breast milk in at least seven studies, raising the possibility that ACE2 is exp...

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Detalles Bibliográficos
Autores principales: Hennighausen, Lothar, Lee, Hye Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474886/
https://www.ncbi.nlm.nih.gov/pubmed/32966801
http://dx.doi.org/10.1016/j.celrep.2020.108199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474886/
https://www.ncbi.nlm.nih.gov/pubmed/32966801
http://dx.doi.org/10.1016/j.celrep.2020.108199

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