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Evolution of dependoparvoviruses across geological timescales—implications for design of AAV-based gene therapy vectors
Endogenous viral elements (EVEs) are genetic remnants of viruses that have integrated into host genomes millions of years ago and retained as heritable elements passed on to offspring until present-day. As a result, EVEs provide an opportunity to analyse the genomes of extinct viruses utilizing thes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474932/ https://www.ncbi.nlm.nih.gov/pubmed/32913662 http://dx.doi.org/10.1093/ve/veaa043 |