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Modification and optimization of the inhibition of HIV-1 cell-to-cell transmission assay

HIV-1 infection is caused by cell-free and cell-associated viruses. Currently most of the assays used to screen potential HIV-1 entry inhibitors focus on the inhibition of cell-free viruses. One assay that is widely employed is the TZM-bl neutralization assay that uses pseudotyped viruses. However,...

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Detalles Bibliográficos
Autores principales: Alexandre, Kabamba, Malatji, Kanyane, Mulaudzi, Takalani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475115/
https://www.ncbi.nlm.nih.gov/pubmed/32923375
http://dx.doi.org/10.1016/j.mex.2020.101014