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The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish

Joubert syndrome is characterized by unique malformation of the cerebellar vermis. More than thirty Joubert syndrome genes have been identified, including ARL13B. However, its role in cerebellar development remains unexplored. We found that knockdown or knockout of arl13b impaired balance and locomo...

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Detalles Bibliográficos
Autores principales: Zhu, Jian, Wang, Han-Tsing, Chen, Yu-Rong, Yan, Ling-Ya, Han, Ying-Ying, Liu, Ling-Yan, Cao, Ying, Liu, Zhi-Zhi, Xu, Hong A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475164/
https://www.ncbi.nlm.nih.gov/pubmed/32812127
http://dx.doi.org/10.1007/s12264-020-00554-y