Cargando…
The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish
Joubert syndrome is characterized by unique malformation of the cerebellar vermis. More than thirty Joubert syndrome genes have been identified, including ARL13B. However, its role in cerebellar development remains unexplored. We found that knockdown or knockout of arl13b impaired balance and locomo...
Autores principales: | Zhu, Jian, Wang, Han-Tsing, Chen, Yu-Rong, Yan, Ling-Ya, Han, Ying-Ying, Liu, Ling-Yan, Cao, Ying, Liu, Zhi-Zhi, Xu, Hong A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475164/ https://www.ncbi.nlm.nih.gov/pubmed/32812127 http://dx.doi.org/10.1007/s12264-020-00554-y |
Ejemplares similares
-
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules
por: He, Kai, et al.
Publicado: (2018) -
Active Transport and Diffusion Barriers Restrict Joubert Syndrome-Associated ARL13B/ARL-13 to an Inv-like Ciliary Membrane Subdomain
por: Cevik, Sebiha, et al.
Publicado: (2013) -
Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
por: Cevik, Sebiha, et al.
Publicado: (2010) -
Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
por: Cevik, Sebiha, et al.
Publicado: (2010) -
ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition
por: Alkanderi, Sumaya, et al.
Publicado: (2018)