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Predicting combinations of immunomodulators to enhance dendritic cell-based vaccination based on a hybrid experimental and computational platform

Dendritic cell (DC)-based vaccines have been largely used in the adjuvant setting for the treatment of cancer, however, despite their proven safety, clinical outcomes still remain modest. In order to improve their efficacy, DC-based vaccines are often combined with one or multiple immunomodulatory a...

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Detalles Bibliográficos
Autores principales: Ahmed, Rita, Crespo, Isaac, Tuyaerts, Sandra, Bekkar, Amel, Graciotti, Michele, Xenarios, Ioannis, Kandalaft, Lana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475195/
https://www.ncbi.nlm.nih.gov/pubmed/32952936
http://dx.doi.org/10.1016/j.csbj.2020.08.001