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Synthesis of (99m)Tc-labeled 2-Mercaptobenzimidazole as a novel radiotracer to diagnose tumor hypoxia

Discovery of (99m)Tc-labeled imidazole derivatives as a potential radiotracer for hypoxic tumor imaging is considered to be of great interest because of non-invasive detection capabilities. 2-Mercaptobenzimidazole (2-MBI) was successfully synthesized, characterized and radiolabeled with [(99m)Tc (CO...

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Detalles Bibliográficos
Autores principales: Rizvi, Syed Faheem Askari, Zhang, Haixia, Mehmood, Sajid, Sanad, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475274/
https://www.ncbi.nlm.nih.gov/pubmed/32862104
http://dx.doi.org/10.1016/j.tranon.2020.100854