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Ligustilide modulates oxidative stress, apoptosis, and immunity to avoid pathological damages in bleomycin induced pulmonary fibrosis rats via inactivating TLR4/MyD88/NF-KB P65

BACKGROUND: Pulmonary fibrosis (PF) is a fatal disease with increasing incidence. Ligustilide (LIG) has been shown to inhibit oxidative stress, apoptosis, and inflammation. Here we investigated the possible effect of LIG on bleomycin-induced PF in Sprague-Dawley rats. METHODS: PF rats were set up th...

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Detalles Bibliográficos
Autores principales: Luo, Shu, Gong, Junzuo, Cao, Xiaoping, Liu, Shiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475441/
https://www.ncbi.nlm.nih.gov/pubmed/32953731
http://dx.doi.org/10.21037/atm-20-4233