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Ligustilide modulates oxidative stress, apoptosis, and immunity to avoid pathological damages in bleomycin induced pulmonary fibrosis rats via inactivating TLR4/MyD88/NF-KB P65
BACKGROUND: Pulmonary fibrosis (PF) is a fatal disease with increasing incidence. Ligustilide (LIG) has been shown to inhibit oxidative stress, apoptosis, and inflammation. Here we investigated the possible effect of LIG on bleomycin-induced PF in Sprague-Dawley rats. METHODS: PF rats were set up th...
Autores principales: | Luo, Shu, Gong, Junzuo, Cao, Xiaoping, Liu, Shiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475441/ https://www.ncbi.nlm.nih.gov/pubmed/32953731 http://dx.doi.org/10.21037/atm-20-4233 |
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