Micheliolide alleviates ankylosing spondylitis (AS) by suppressing the activation of the NLRP3 inflammasome and maintaining the balance of Th1/Th2 via regulating the NF-κB signaling pathway

BACKGROUND: Ankylosing spondylitis (AS) is a common form of inflammatory arthritis. Micheliolide (MCL), a sesquiterpene lactone, is reportedly involved in the alleviation of inflammatory response. This study aimed to investigate the mechanism of MCL in the treatment of AS. METHODS: Mice were randoml...

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Detalles Bibliográficos
Autores principales: Tian, Zhong-Gu, Yao, Miaomiao, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475468/
https://www.ncbi.nlm.nih.gov/pubmed/32953791
http://dx.doi.org/10.21037/atm-20-4987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475468/
https://www.ncbi.nlm.nih.gov/pubmed/32953791
http://dx.doi.org/10.21037/atm-20-4987

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