MID1 and MID2 regulate cell migration and epithelial-mesenchymal transition via modulating Wnt/β-catenin signaling

BACKGROUND: The ubiquitin E3 ligase activity has been ascribed to MID1, the causative gene of X-linked OS, and its homologue, MID2. Both alpha4, the common MID protein partner, and PP2Ac in MID-alpha4-PP2Ac complexes can be ubiquitylated. Ubiquitylation of alpha4 converted its function toward PP2Ac...

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Detalles Bibliográficos
Autores principales: Qiao, Yingying, Zhou, Yuan, Song, Chao, Zhang, Xin, Zou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475493/
https://www.ncbi.nlm.nih.gov/pubmed/32953821
http://dx.doi.org/10.21037/atm-20-5583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475493/
https://www.ncbi.nlm.nih.gov/pubmed/32953821
http://dx.doi.org/10.21037/atm-20-5583

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