STAT1-p53-p21axis-dependent stress-induced progression of chronic nephrosis in adriamycin-induced mouse model

BACKGROUND: Chronic nephrosis (CN) is an aging-related disease with high mortality. Signal transduction and transcriptional activator 1 (STAT1) protein promotes senescence in human glomerular mesangial cells (HMCs), but whether it affects the progression of adriamycin (ADR)-induced CN in vivo remain...

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Detalles Bibliográficos
Autores principales: Wei, Hua, Wang, Jiali, Liang, Zhaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475511/
https://www.ncbi.nlm.nih.gov/pubmed/32953802
http://dx.doi.org/10.21037/atm-20-5167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475511/
https://www.ncbi.nlm.nih.gov/pubmed/32953802
http://dx.doi.org/10.21037/atm-20-5167

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