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Leaving no-one behind: how CENP-E facilitates chromosome alignment

Chromosome alignment and biorientation is essential for mitotic progression and genomic stability. Most chromosomes align at the spindle equator in a motor-independent manner. However, a subset of polar kinetochores fail to bi-orient and require a microtubule motor-based transport mechanism to move...

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Detalles Bibliográficos
Autores principales: Craske, Benjamin, Welburn, Julie P.I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475649/
https://www.ncbi.nlm.nih.gov/pubmed/32347304
http://dx.doi.org/10.1042/EBC20190073