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CENP-A nucleosome—a chromatin-embedded pedestal for the centromere: lessons learned from structural biology

The centromere is a chromosome locus that directs equal segregation of chromosomes during cell division. A nucleosome containing the histone H3 variant CENP-A epigenetically defines the centromere. Here, we summarize findings from recent structural biology studies, including several CryoEM structure...

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Detalles Bibliográficos
Autores principales: Ali-Ahmad, Ahmad, Sekulić, Nikolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475651/
https://www.ncbi.nlm.nih.gov/pubmed/32720682
http://dx.doi.org/10.1042/EBC20190074