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Aberrant integrin αv and α5 expression in prostate adenocarcinomas and bone-metastases is consistent with a bone-colonizing phenotype

BACKGROUND: Collaborative signaling between fibronectin-binding αv and α5 integrins has been implicated in the lethal dissemination of prostate cancer in the bone-metastatic niche, the major source of morbidity and mortality in the disease. METHODS: We assessed the frequency and pattern of expressio...

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Detalles Bibliográficos
Autores principales: Connell, Brendan, Kopach, Pavel, Ren, Wenying, Joshi, Raghav, Naber, Stephen, Zhou, Ming, Mathew, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475658/
https://www.ncbi.nlm.nih.gov/pubmed/32944524
http://dx.doi.org/10.21037/tau-19-763