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Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway

BACKGROUND: To study the protective effect of berberine (BBR) on cisplatin-induced acute kidney injury (AKI) and its effect on mitophagy. METHODS: (I) Male C57BL/6 mice aged 6–8 weeks were randomly divided into control group (saline), cisplatin group (cisplatin), and cisplatin + BBR (5, 10 mg/kg) gr...

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Detalles Bibliográficos
Autores principales: Qi, Jieying, Xue, Qi, Kuang, Liuyan, Xie, Lifen, Luo, Ren, Nie, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475663/
https://www.ncbi.nlm.nih.gov/pubmed/32944532
http://dx.doi.org/10.21037/tau-20-1129