YQFM Alleviates Side Effects Caused by Dasatinib through the ROCK/MLC Pathway in Mice

Dasatinib, as a second-generation broad-spectrum tyrosine kinase inhibitor, presents an antitumor effect by inhibiting tyrosine kinases. However, dasatinib causes serious side effects, such as gastrointestinal bleeding and liver toxicity, possibly through the activation of ROCK kinase and MLC phosph...

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Detalles Bibliográficos
Autores principales: Liu, Yuankai, Dai, Yujie, Xu, Han, Zhou, Qianliu, Li, Fang, Yu, Boyang, Zhang, Yuanyuan, Kou, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475753/
https://www.ncbi.nlm.nih.gov/pubmed/32908560
http://dx.doi.org/10.1155/2020/4646029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475753/
https://www.ncbi.nlm.nih.gov/pubmed/32908560
http://dx.doi.org/10.1155/2020/4646029

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