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Single-cell RNA-seq reveals the immune escape and drug resistance mechanisms of mantle cell lymphoma

Objective: Mantle cell lymphoma (MCL) is a rare subtype of non-Hodgkin lymphoma (NHL) with high heterogeneity and a high recurrence rate. How heterogenous cell populations contribute to relapse remains to be elucidated. Methods: We performed single cell RNA sequencing (scRNA-seq) on approximately 4,...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Mo, Steven, Li, Xin, He, Yingzhi, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476085/
https://www.ncbi.nlm.nih.gov/pubmed/32944402
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0073