Higher burden of rare frameshift indels in genes related to synaptic transmission separate familial hemiplegic migraine from common types of migraine

BACKGROUND: Familial hemiplegic migraine (FHM) is a rare form of migraine with aura that often has an autosomal dominant mode of inheritance. Rare mutations in the CACNA1A, ATP1A2 and SCN1A genes can all cause FHM revealing genetic heterogeneity in the disorder. Furthermore, only a small subset of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Rasmussen, Andreas Hoiberg, Olofsson, Isa, Chalmer, Mona Ameri, Olesen, Jes, Hansen, Thomas Folkmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Genotype-Phenotype Correlations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476275/
https://www.ncbi.nlm.nih.gov/pubmed/31980564
http://dx.doi.org/10.1136/jmedgenet-2019-106640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476275/
https://www.ncbi.nlm.nih.gov/pubmed/31980564
http://dx.doi.org/10.1136/jmedgenet-2019-106640

Ejemplares similares