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Tunneling Nanotubes Mediate Adaptation of Glioblastoma Cells to Temozolomide and Ionizing Radiation Treatment

Glioblastoma (GBM) is the most prevalent and aggressive tumor in the central nervous system. Surgical resection followed by concurrent radiotherapy (ionizing radiation [IR]) and temozolomide (TMZ) is the standard of care for GBM. However, a large subset of patients offer resistance or become adapted...

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Detalles Bibliográficos
Autores principales: Valdebenito, Silvana, Audia, Alessandra, Bhat, Krishna P.L., Okafo, George, Eugenin, Eliseo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476317/
https://www.ncbi.nlm.nih.gov/pubmed/32882515
http://dx.doi.org/10.1016/j.isci.2020.101450