The Novel Angiotensin-(1–7) Analog, A-1317, Improves Insulin Resistance by Restoring Pancreatic β-Cell Functionality in Rats With Metabolic Syndrome

In previous studies we have shown that oral Ang-(1–7) has a beneficial therapeutic effect on cardiometabolic disturbances present in metabolic syndrome (MetS). Based on the fact that Ang-(1–7) acts through release of nitric oxide (NO), a new peptide, A-1317 was engineered adding the amino acid L-Arg...

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Detalles Bibliográficos
Autores principales: Barbosa, Maria Andréa, Barbosa, Claudiane Maria, Lima, Taynara Carolina, dos Santos, Robson Augusto Souza, Alzamora, Andréia Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476374/
https://www.ncbi.nlm.nih.gov/pubmed/32982727
http://dx.doi.org/10.3389/fphar.2020.01263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476374/
https://www.ncbi.nlm.nih.gov/pubmed/32982727
http://dx.doi.org/10.3389/fphar.2020.01263

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