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Structural-based virtual screening and in vitro assays for small molecules inhibiting the feline coronavirus 3CL protease as a surrogate platform for coronaviruses

Feline infectious peritonitis (FIP) which is caused by feline infectious peritonitis virus (FIPV), a variant of feline coronavirus (FCoV), is a member of family Coronaviridae, together with severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-C...

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Detalles Bibliográficos
Autores principales: Theerawatanasirikul, Sirin, Kuo, Chih Jung, Phecharat, Nanthawan, Chootip, Jullada, Lekcharoensuk, Chalermpol, Lekcharoensuk, Porntippa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476565/
https://www.ncbi.nlm.nih.gov/pubmed/32910955
http://dx.doi.org/10.1016/j.antiviral.2020.104927