Lipophilicity trends upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl groups

A systematic comparison of lipophilicity modulations upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl substituents, at a single carbon atom, is provided using directly comparable, and easily accessible model compounds. In addition, comparison with relevant linear chain derivatives is provi...

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Detalles Bibliográficos
Autores principales: Jeffries, Benjamin, Wang, Zhong, Troup, Robert I, Goupille, Anaïs, Le Questel, Jean-Yves, Fallan, Charlene, Scott, James S, Chiarparin, Elisabetta, Graton, Jérôme, Linclau, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476584/
https://www.ncbi.nlm.nih.gov/pubmed/32952731
http://dx.doi.org/10.3762/bjoc.16.182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476584/
https://www.ncbi.nlm.nih.gov/pubmed/32952731
http://dx.doi.org/10.3762/bjoc.16.182

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