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Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition

PURPOSE: Diabetic retinopathy (DR) is a microvascular complication caused by prolonged hyperglycemia and characterized by leaky retinal vasculature and ischemia-induced angiogenesis. Vitreous humor is a gel-like biofluid in the posterior segment of the eye between the lens and the retina. Disease-re...

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Detalles Bibliográficos
Autores principales: Robinson, Rebekah, Youngblood, Hannah, Iyer, Hersha, Bloom, Justin, Lee, Tae Jin, Chang, Luke, Lukowski, Zachary, Zhi, Wenbo, Sharma, Ashok, Sharma, Shruti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476668/
https://www.ncbi.nlm.nih.gov/pubmed/32870245
http://dx.doi.org/10.1167/iovs.61.11.2