Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections

BACKGROUND: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Monosomy 3 and BAP1 mutation are strong prognostic factors predicting metastatic risk in UM. Nuclear BAP1 (nBAP1) expression is a close immunohistochemical surrogate for both genetic alterations. Not all lab...

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Detalles Bibliográficos
Autores principales: Zhang, Hongrun, Kalirai, Helen, Acha-Sagredo, Amelia, Yang, Xiaoyun, Zheng, Yalin, Coupland, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476670/
https://www.ncbi.nlm.nih.gov/pubmed/32953248
http://dx.doi.org/10.1167/tvst.9.2.50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476670/
https://www.ncbi.nlm.nih.gov/pubmed/32953248
http://dx.doi.org/10.1167/tvst.9.2.50

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