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Population bias in somatic measurement of microsatellite instability status

Microsatellite instability (MSI) is a key secondary effect of a defective DNA mismatch repair mechanism resulting in incorrectly replicated microsatellites in many malignant tumors. Historically, MSI detection has been performed by fragment analysis (FA) on a panel of representative genomic markers....

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Detalles Bibliográficos
Autores principales: Saul, Michelle, Poorman, Kelsey, Tae, Hongseok, Vanderwalde, Ari, Stafford, Phillip, Spetzler, David, Korn, Wolfgang M., Gatalica, Zoran, Swensen, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476819/
https://www.ncbi.nlm.nih.gov/pubmed/32644297
http://dx.doi.org/10.1002/cam4.3294