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Streptavidin Promotes DNA Binding and Activation of cGAS to Enhance Innate Immunity
cGAS/STING signaling plays an essential role in sensing cytosolic DNA. cGAS activity is regulated by posttranslational modifications and binding partners. cGAS interactome largely includes mammalian or viral proteins. Whether and how bacterial proteins bind cGAS to modulate innate immunity remain el...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476851/ https://www.ncbi.nlm.nih.gov/pubmed/32861998 http://dx.doi.org/10.1016/j.isci.2020.101463 |