Streptavidin Promotes DNA Binding and Activation of cGAS to Enhance Innate Immunity

cGAS/STING signaling plays an essential role in sensing cytosolic DNA. cGAS activity is regulated by posttranslational modifications and binding partners. cGAS interactome largely includes mammalian or viral proteins. Whether and how bacterial proteins bind cGAS to modulate innate immunity remain el...

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Detalles Bibliográficos
Autores principales: Zhang, Yanqiong, Ma, Zhe, Wang, Ying, Boyer, Joshua, Ni, Guoxin, Cheng, Liang, Su, Siyuan, Zhang, Zhigang, Zhu, Zhichuan, Qian, Jiayi, Su, Lishan, Zhang, Qi, Damania, Blossom, Liu, Pengda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476851/
https://www.ncbi.nlm.nih.gov/pubmed/32861998
http://dx.doi.org/10.1016/j.isci.2020.101463

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