Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease

In Alzheimer's disease (AD), decreases in the amount and synaptic localization of AMPA receptors (AMPARs) result in weakened synaptic activity and dysfunction in synaptic plasticity, leading to impairments in cognitive functions. We have previously found that AMPARs are subject to lysine acetyl...

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Detalles Bibliográficos
Autores principales: O'Connor, Margaret, Shentu, Yang-Ping, Wang, Guan, Hu, Wen-Ting, Xu, Zhen-Dong, Wang, Xiao-Chuan, Liu, Rong, Man, Heng-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476873/
https://www.ncbi.nlm.nih.gov/pubmed/32861999
http://dx.doi.org/10.1016/j.isci.2020.101465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476873/
https://www.ncbi.nlm.nih.gov/pubmed/32861999
http://dx.doi.org/10.1016/j.isci.2020.101465

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