Cargando…

Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease

In Alzheimer's disease (AD), decreases in the amount and synaptic localization of AMPA receptors (AMPARs) result in weakened synaptic activity and dysfunction in synaptic plasticity, leading to impairments in cognitive functions. We have previously found that AMPARs are subject to lysine acetyl...

Descripción completa

Detalles Bibliográficos
Autores principales:	O'Connor, Margaret, Shentu, Yang-Ping, Wang, Guan, Hu, Wen-Ting, Xu, Zhen-Dong, Wang, Xiao-Chuan, Liu, Rong, Man, Heng-Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476873/ https://www.ncbi.nlm.nih.gov/pubmed/32861999 http://dx.doi.org/10.1016/j.isci.2020.101465

Ejemplares similares

AMPA Receptor Trafficking in Homeostatic Synaptic Plasticity: Functional Molecules and Signaling Cascades
por: Wang, Guan, et al.
Publicado: (2012)

Hormonal Regulation of AMPA Receptor Trafficking and Memory Formation
por: Krugers, Harmen J., et al.
Publicado: (2009)

AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking
por: Bissen, Diane, et al.
Publicado: (2019)

Retrieval-extinction of drug memory requires AMPA receptor trafficking
por: Lv, Xinyou, et al.
Publicado: (2022)

AMPA Receptor Trafficking for Postsynaptic Potentiation
por: Park, Mikyoung
Publicado: (2018)

Cortical development of AMPA receptor trafficking proteins
por: Murphy, Kathryn M., et al.
Publicado: (2012)

Actin-dependent mechanisms in AMPA receptor trafficking
por: Hanley, Jonathan G.
Publicado: (2014)

Regulation of AMPA Receptor Trafficking by Protein Ubiquitination
por: Widagdo, Jocelyn, et al.
Publicado: (2017)

AMPA Receptor Trafficking in Natural and Pathological Aging
por: Jurado, Sandra
Publicado: (2018)

Coordination of AMPA receptor trafficking by Rab GTPases
por: Hausser, Angelika, et al.
Publicado: (2017)

Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity
por: Liu, Ke, et al.
Publicado: (2016)

Amyloid-β-Induced Dysregulation of AMPA Receptor Trafficking
por: Guntupalli, Sumasri, et al.
Publicado: (2016)

PACSIN1 regulates the dynamics of AMPA receptor trafficking
por: Widagdo, Jocelyn, et al.
Publicado: (2016)

AMPA receptor trafficking and its role in heterosynaptic plasticity
por: Antunes, G., et al.
Publicado: (2018)

Dysfunction of Glutamatergic Synaptic Transmission in Depression: Focus on AMPA Receptor Trafficking
por: He, Jin-Gang, et al.
Publicado: (2022)

A role for sorting nexin 27 in AMPA receptor trafficking
por: Loo, Li Shen, et al.
Publicado: (2014)

Palmitoylation-mediated synaptic regulation of AMPA receptor trafficking and function
por: Sohn, Heesung, et al.
Publicado: (2019)

Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs
por: Sanderson, Thomas M, et al.
Publicado: (2011)

Rapid and bi-directional regulation of AMPA receptor phosphorylation and trafficking by JNK
por: Thomas, Gareth M, et al.
Publicado: (2008)

AMPA receptor trafficking and the mechanisms underlying synaptic plasticity and cognitive aging
por: Henley, Jeremy M., et al.
Publicado: (2013)

Proteins Involved in the Trafficking and Functional Synaptic Expression of AMPA and KA Receptors
por: De La Rue, Sarah A., et al.
Publicado: (2002)

AMPA receptor trafficking and LTP: Carboxy-termini, amino-termini and TARPs
por: Díaz-Alonso, Javier, et al.
Publicado: (2021)

Modulating AMPA receptors makes memories special
por: Dove, Alan W.
Publicado: (2003)

Reversal of aging-related emotional memory deficits by norepinephrine via regulating the stability of surface AMPA receptors
por: Luo, Yi, et al.
Publicado: (2015)

Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking
por: Du, Jing, et al.
Publicado: (2004)

Modulation of dendritic AMPA receptor mRNA trafficking by RNA splicing and editing
por: La Via, Luca, et al.
Publicado: (2013)

Synaptic activity regulates AMPA receptor trafficking through different recycling pathways
por: Zheng, Ning, et al.
Publicado: (2015)

CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer’s Disease
por: Shentu, Yang-Ping, et al.
Publicado: (2018)

Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
por: Alhowail, Ahmad H., et al.
Publicado: (2021)

S-palmitoylation regulates AMPA receptors trafficking and function: a novel insight into synaptic regulation and therapeutics
por: Han, Jun, et al.
Publicado: (2015)

Group II Metabotropic Glutamate Receptor Agonist LY379268 Regulates AMPA Receptor Trafficking in Prefrontal Cortical Neurons
por: Wang, Min-Juan, et al.
Publicado: (2013)

Inhibition of AMPA receptor trafficking at hippocampal synapses by β-amyloid oligomers: the mitochondrial contribution
por: Rui, Yanfang, et al.
Publicado: (2010)

Pathogenic Mechanism of an Autism-Associated Neuroligin Mutation Involves Altered AMPA-Receptor Trafficking
por: Chanda, Soham, et al.
Publicado: (2015)

A Multisubcellular Compartment Model of AMPA Receptor Trafficking for Neuromodulation of Hebbian Synaptic Plasticity
por: Mihalas, Stefan, et al.
Publicado: (2021)

Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellum
por: Coombs, I.D., et al.
Publicado: (2009)

Input-specific homeostatic regulation of AMPA receptor accumulation at central synapses
por: Hou, Qingming, et al.
Publicado: (2012)

AMPA Receptors: A Key Piece in the Puzzle of Memory Retrieval
por: Pereyra, Magdalena, et al.
Publicado: (2021)

Uncorking AMPA receptors
por: Sedwick, Caitlin
Publicado: (2018)

Resensitizing AMPA receptors
por: Short, Ben
Publicado: (2019)

Pi4KIIα Regulates Unconditioned Stimulus-Retrieval-Induced Fear Memory Reconsolidation through Endosomal Trafficking of AMPA Receptors
por: Guo, Hongling, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tt1031vsffmtgqvuentu896rpk