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Neuronal Selection Based on Relative Fitness Comparison Detects and Eliminates Amyloid-β-Induced Hyperactive Neurons in Drosophila

During adult life, damaged but viable neurons can accumulate in the organism, creating increasingly heterogeneous and dysfunctional neural circuits. One intriguing example is the aberrant increased activity of cerebral networks detected in vulnerable brain regions during preclinical stages of Alzhei...

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Detalles Bibliográficos
Autores principales: Coelho, Dina S., Moreno, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476875/
https://www.ncbi.nlm.nih.gov/pubmed/32866827
http://dx.doi.org/10.1016/j.isci.2020.101468