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Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity

OBJECTIVES: Diet-driven obesity is increasingly widespread. Its consequences pose major challenges to human health and health care systems. There are MAP kinase-interacting kinases (MNKs) in mice, MNK1 and MNK2. Studies have demonstrated that mice lacking either MNK1 or MNK2 were partially protected...

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Detalles Bibliográficos
Autores principales: Sandeman, Lauren Y., Kang, Wan Xian, Wang, Xuemin, Jensen, Kirk B., Wong, Derick, Bo, Tao, Gao, Ling, Zhao, Jiajun, Byrne, Christopher D., Page, Amanda J., Proud, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476876/
https://www.ncbi.nlm.nih.gov/pubmed/32712434
http://dx.doi.org/10.1016/j.molmet.2020.101054