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Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity
OBJECTIVES: Diet-driven obesity is increasingly widespread. Its consequences pose major challenges to human health and health care systems. There are MAP kinase-interacting kinases (MNKs) in mice, MNK1 and MNK2. Studies have demonstrated that mice lacking either MNK1 or MNK2 were partially protected...
Autores principales: | Sandeman, Lauren Y., Kang, Wan Xian, Wang, Xuemin, Jensen, Kirk B., Wong, Derick, Bo, Tao, Gao, Ling, Zhao, Jiajun, Byrne, Christopher D., Page, Amanda J., Proud, Christopher G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476876/ https://www.ncbi.nlm.nih.gov/pubmed/32712434 http://dx.doi.org/10.1016/j.molmet.2020.101054 |
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