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Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity

All forms of diabetes mellitus involve the loss or dysfunction of pancreatic beta cells, with the former predominating in type 1 diabetes and the latter in type 2 diabetes. Deeper understanding of the coupling mechanisms that link glucose metabolism in these cells to the control of insulin secretion...

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Detalles Bibliográficos
Autores principales: Rutter, Guy A., Georgiadou, Eleni, Martinez-Sanchez, Aida, Pullen, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476987/
https://www.ncbi.nlm.nih.gov/pubmed/32894309
http://dx.doi.org/10.1007/s00125-020-05205-5