A Coarse-Grained Methodology Identifies Intrinsic Mechanisms That Dissociate Interacting Protein Pairs

We address the problem of triggering dissociation events between proteins that have formed a complex. We have collected a set of 25 non-redundant, functionally diverse protein complexes having high-resolution three-dimensional structures in both the unbound and bound forms. We unify elastic network...

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Detalles Bibliográficos
Autores principales: Abdizadeh, Haleh, Jalalypour, Farzaneh, Atilgan, Ali Rana, Atilgan, Canan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477071/
https://www.ncbi.nlm.nih.gov/pubmed/33195399
http://dx.doi.org/10.3389/fmolb.2020.00210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477071/
https://www.ncbi.nlm.nih.gov/pubmed/33195399
http://dx.doi.org/10.3389/fmolb.2020.00210

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