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A Coarse-Grained Methodology Identifies Intrinsic Mechanisms That Dissociate Interacting Protein Pairs
We address the problem of triggering dissociation events between proteins that have formed a complex. We have collected a set of 25 non-redundant, functionally diverse protein complexes having high-resolution three-dimensional structures in both the unbound and bound forms. We unify elastic network...
Autores principales: | Abdizadeh, Haleh, Jalalypour, Farzaneh, Atilgan, Ali Rana, Atilgan, Canan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477071/ https://www.ncbi.nlm.nih.gov/pubmed/33195399 http://dx.doi.org/10.3389/fmolb.2020.00210 |
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