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Flavin dependency undermines proteome stability, lipid metabolism and cellular proliferation during vitamin B2 deficiency

Tumor cells adapt their metabolism to meet the energetic and anabolic requirements of high proliferation and invasiveness. The metabolic addiction has motivated the development of therapies directed at individual biochemical nodes. However, currently there are few possibilities to target multiple en...

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Detalles Bibliográficos
Autores principales: Martínez-Limón, Adrían, Calloni, Giulia, Ernst, Robert, Vabulas, R. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477094/
https://www.ncbi.nlm.nih.gov/pubmed/32895367
http://dx.doi.org/10.1038/s41419-020-02929-5