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TRPV6 calcium channel directs homeostasis of the mammary epithelial sheets and controls epithelial mesenchymal transition

Epithelial integrity is lost upon cancer progression as cancer cells detach from the primary tumor site and start to invade to the surrounding tissues. Invasive cancers of epithelial origin often express altered levels of TRP-family cation channels. Upregulation of TRPV6 Ca(2+)-channel has been asso...

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Detalles Bibliográficos
Autores principales: Kärki, Tytti, Rajakylä, Eeva Kaisa, Acheva, Anna, Tojkander, Sari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477193/
https://www.ncbi.nlm.nih.gov/pubmed/32895467
http://dx.doi.org/10.1038/s41598-020-71645-z