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Assembly intermediates of orthoreovirus captured in the cell

Traditionally, molecular assembly pathways for viruses are inferred from high resolution structures of purified stable intermediates, low resolution images of cell sections and genetic approaches. Here, we directly visualise an unsuspected ‘single shelled’ intermediate for a mammalian orthoreovirus...

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Detalles Bibliográficos
Autores principales: Sutton, Geoff, Sun, Dapeng, Fu, Xiaofeng, Kotecha, Abhay, Hecksel, Corey W., Clare, Daniel K., Zhang, Peijun, Stuart, David I., Boyce, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477198/
https://www.ncbi.nlm.nih.gov/pubmed/32895380
http://dx.doi.org/10.1038/s41467-020-18243-9