Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission

In rodent models of type 2 diabetes (T2D), sustained remission of hyperglycemia can be induced by a single intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1), and the mediobasal hypothalamus (MBH) was recently implicated as the brain area responsible for this effect. To bet...

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Detalles Bibliográficos
Autores principales: Bentsen, Marie A., Rausch, Dylan M., Mirzadeh, Zaman, Muta, Kenjiro, Scarlett, Jarrad M., Brown, Jenny M., Herranz-Pérez, Vicente, Baquero, Arian F., Thompson, Jonatan, Alonge, Kimberly M., Faber, Chelsea L., Kaiyala, Karl J., Bennett, Camdin, Pyke, Charles, Ratner, Cecilia, Egerod, Kristoffer L., Holst, Birgitte, Meek, Thomas H., Kutlu, Burak, Zhang, Yu, Sparso, Thomas, Grove, Kevin L., Morton, Gregory J., Kornum, Birgitte R., García-Verdugo, José-Manuel, Secher, Anna, Jorgensen, Rasmus, Schwartz, Michael W., Pers, Tune H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477234/
https://www.ncbi.nlm.nih.gov/pubmed/32895383
http://dx.doi.org/10.1038/s41467-020-17720-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477234/
https://www.ncbi.nlm.nih.gov/pubmed/32895383
http://dx.doi.org/10.1038/s41467-020-17720-5

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