Exploiting Sphingo- and Glycerophospholipid Impairment to Select Effective Drugs and Biomarkers for CMT1A

In Charcot–Marie–Tooth type 1A (CMT1A), Schwann cells exhibit a preponderant transcriptional deficiency of genes involved in lipid biosynthesis. This perturbed lipid metabolism affects the peripheral nerve physiology and the structure of peripheral myelin. Nevertheless, the identification and functi...

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Detalles Bibliográficos
Autores principales: Visigalli, Davide, Capodivento, Giovanna, Basit, Abdul, Fernández, Roberto, Hamid, Zeeshan, Pencová, Barbora, Gemelli, Chiara, Marubbi, Daniela, Pastorino, Cecilia, Luoma, Adrienne M., Riekel, Christian, Kirschner, Daniel A., Schenone, Angelo, Fernández, José A., Armirotti, Andrea, Nobbio, Lucilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477391/
https://www.ncbi.nlm.nih.gov/pubmed/32982928
http://dx.doi.org/10.3389/fneur.2020.00903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477391/
https://www.ncbi.nlm.nih.gov/pubmed/32982928
http://dx.doi.org/10.3389/fneur.2020.00903

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