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ZIC2 promotes cancer stem cell traits via up-regulating OCT4 expression in lung adenocarcinoma cells

Background: Accumulating evidence has revealed the importance of cancer stem cells (CSCs) in self-renewal and chemoresistance. Previous studies reported high expression of ZIC2 was closely associated with tumorigenesis and CSC traits. However, the role of ZIC2 as a crucial factor for regulating CSC...

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Detalles Bibliográficos
Autores principales: Wei-Hua, Wang, Ning, Zhou, Qian, Chen, Dao-Wen, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477430/
https://www.ncbi.nlm.nih.gov/pubmed/32922547
http://dx.doi.org/10.7150/jca.44367