Moxidectin induces Cytostatic Autophagic Cell Death of Glioma Cells through inhibiting the AKT/mTOR Signalling Pathway

Moxidectin (MOX), a broad-spectrum antiparasitic drug, has been characterized as a potential anti-glioma agent. The main objective of this study was to explore autophagy induced by MOX in glioma U251 and C6 cells, and the deep underlying molecular mechanisms. In addition, the effects of autophagy on...

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Detalles Bibliográficos
Autores principales: Liu, Jingjing, Liang, Hongsheng, Khilji, Saadia, Li, Haitao, Song, Dandan, Chen, Chen, Wang, Xiaoxing, Zhang, Yiwei, Zhao, Ning, Li, Xina, Gao, Aili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477456/
https://www.ncbi.nlm.nih.gov/pubmed/32913473
http://dx.doi.org/10.7150/jca.46697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477456/
https://www.ncbi.nlm.nih.gov/pubmed/32913473
http://dx.doi.org/10.7150/jca.46697

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