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Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation
Substance abuse disorders are linked to alteration of circadian rhythms, although the molecular and neuronal pathways implicated have not been fully elucidated. Addictive drugs, such as cocaine, induce a rapid increase of dopamine levels in the brain. Here, we show that acute administration of cocai...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477550/ https://www.ncbi.nlm.nih.gov/pubmed/32895370 http://dx.doi.org/10.1038/s41467-020-18200-6 |