Preclinical efficacy of CIGB-300, an anti-CK2 peptide, on breast cancer metastasic colonization

CK2 is a serine/threonine kinase that is overexpressed in breast cancer and its inhibition is associated to reduced tumor growth and disease progression. CIGB-300 is an antitumor peptide with a novel mechanism of action, since it binds to protein kinase CK2 catalytic subunit alpha and to CK2 substra...

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Detalles Bibliográficos
Autores principales: Gottardo, Maria F., Capobianco, Carla S., Sidabra, Johanna E., Garona, Juan, Perera, Yasser, Perea, Silvio E., Alonso, Daniel F., Farina, Hernan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477577/
https://www.ncbi.nlm.nih.gov/pubmed/32895446
http://dx.doi.org/10.1038/s41598-020-71854-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477577/
https://www.ncbi.nlm.nih.gov/pubmed/32895446
http://dx.doi.org/10.1038/s41598-020-71854-6

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