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Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

BACKGROUND & OBJECTIVE: Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme “Thiopurine S-methyl transferase” (TPMT). Various variants of this enzyme may have decreased activity leadin...

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Detalles Bibliográficos
Autores principales: Mokhtari, Maral, Mostanbet, Farzaneh, Nekooee Fard, Saideh, Shekarkhar, Golsa, Sepaskhah, Mozhdeh, Sadati, Maryam Sadat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477690/
https://www.ncbi.nlm.nih.gov/pubmed/32944042
http://dx.doi.org/10.30699/ijp.2020.121365.2320