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Simulation-based assessment of model selection criteria during the application of benchmark dose method to quantal response data

BACKGROUND: To employ the benchmark dose (BMD) method in toxicological risk assessment, it is critical to understand how the BMD lower bound for reference dose calculation is selected following statistical fitting procedures of multiple mathematical models. The purpose of this study was to compare t...

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Detalles Bibliográficos
Autores principales: Yoshii, Keita, Nishiura, Hiroshi, Inoue, Kaoru, Yamaguchi, Takayuki, Hirose, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477879/
https://www.ncbi.nlm.nih.gov/pubmed/32753042
http://dx.doi.org/10.1186/s12976-020-00131-w