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Simulation-based assessment of model selection criteria during the application of benchmark dose method to quantal response data
BACKGROUND: To employ the benchmark dose (BMD) method in toxicological risk assessment, it is critical to understand how the BMD lower bound for reference dose calculation is selected following statistical fitting procedures of multiple mathematical models. The purpose of this study was to compare t...
Autores principales: | Yoshii, Keita, Nishiura, Hiroshi, Inoue, Kaoru, Yamaguchi, Takayuki, Hirose, Akihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477879/ https://www.ncbi.nlm.nih.gov/pubmed/32753042 http://dx.doi.org/10.1186/s12976-020-00131-w |
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